Endemic transmission of HTLV-2 in blood donors from São Luís do Maranhão, northeastern Brazil: report of two asymptomatic individuals
نویسندگان
چکیده
Human T-cell lymphotropic virus 1 and 2 (HTLV-1, HTLV-2) belong to the Retroviridae family, genus Deltaretrovirus1,2 and have similar biological properties, with tropism of T lymphocytes. They are associated with rare lymphoproliferative diseases.3,4 Brazil has a high seroprevalence of HTLV-1/2 among blood donors. The mean prevalence ranges from 0.4/1000 in Florianópolis to 10.0/1000 in São Luís do Maranhão.5 The first case of HTLV-2 was described in 1982 in a patient with hairy cell leukemia.6 The virus is acquired through unprotected sexual intercourse, by vertical transmission and, in Europe and North America, infection is associated with intravenous drug users. HTLV-2 is endemic in some Indian villages and urban populations in northern Brazil,7 in the state of São Paulo and in the central western region of the country.8 HTLV-2 can be classified into four major subtypes: HTLV-2a, HTLV-2b, HTLV-2c and HTLV-2d by molecular
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BACKGROUND Infection with human T-lymphotropic virus 1 or 2 (HTLV-1/2) is a major health problem. There is a public health policy defining measures for state hematology and hemotherapy centers in Brazil, in order to avoid virus transmission through blood donors. OBJECTIVE This study aimed to evaluate the seroprevalence of HTLV -1/2 in blood donors in the State of Maranhão, Brazil, during rout...
متن کاملسرواپیدمیولوژی ویروس لنفوتروپیک سلول T انسانی(HTLV) در اهداکنندگان خون در شهر مشهد، سالهای 89-1388
Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cause of two major diseases : Adult T cell Leukemia-Lymphoma and Tropical Spastic Paraparasia and Myelopathy associated with HTLV-I. Disease transmission is possible during unsafe sexual contact, blood transfusion and vertical transmission method. Blood safety and minimizing the risk of transfusion transmitted infections are th...
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